Nonstructural Proteins of Alphavirus—Potential Targets for Drug Development
نویسندگان
چکیده
منابع مشابه
Nonstructural Proteins of Alphavirus—Potential Targets for Drug Development
Alphaviruses are enveloped, positive single-stranded RNA viruses, typically transmitted by arthropods. They often cause arthralgia or encephalitic diseases in infected humans and there is currently no targeted antiviral treatment available. The re-emergence of alphaviruses in Asia, Europe, and the Americas over the last decade, including chikungunya and o'nyong'nyong viruses, have intensified t...
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By the end of 2004, more than 20 HIV-1 vaccine candidates will have entered clinical testing in at least 30 trials worldwide. Almost half of these vaccines include nonstructural HIV-1 gene products. This represents an important innovation in the HIV vaccine field, because until 9 years ago not even preclinical testing in small animal models had been carried out with such immunogens. This review...
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ژورنال
عنوان ژورنال: Viruses
سال: 2018
ISSN: 1999-4915
DOI: 10.3390/v10020071